Infusion Doses
Live ranges by weight + drip rate at standard concentrations.
Common ICU Antibiotics
Empiric doses with renal adjustment by CrCl.
Hemodynamics
MAP, shock index, CPP, pressor load, QTc.
QTc Calculator
Blood Pressure
Cerebral Perfusion
Norepi Equivalents
Ventilator
PBW-based TV, Berlin ARDS, driving pressure, ROX index.
ROX Index (HFNC success)
Tidal Volume (Predicted BW)
Oxygenation (P/F & SF)
Driving Pressure & Compliance
Weaning Readiness & RSBI
SBT + extubation checklist (tap)
- SBT eligibility: cause of resp failure resolving · FiO₂ ≤ 0.5 and PEEP ≤ 8 · P/F > 150 · haemodynamic stability (MAP ≥ 65 on minimal pressors) · adequate cough / airway reflex · GCS adequate / RASS − 1 to + 1 · pH ≥ 7.30 · Hb ≥ 7 · electrolytes OK.
- SBT settings: PS 0 – 8 cmH₂O (or T-piece) + PEEP 0 – 5 × 30 – 120 min. CPAP alone acceptable.
- Pass criteria: RSBI < 105 · RR < 35 · SpO₂ ≥ 90 (or FiO₂ unchanged) · HR < 140 (and no > 20 % change) · SBP 90 – 180 (no > 20 % change) · no respiratory distress (accessory muscles, diaphoresis, agitation).
- Cuff-leak test (high-risk airway): leak < 110 mL or < 10 – 24 % of TV → high stridor risk → dexamethasone 20 mg or 4 × 5 mg q 6 h × 24 h before extubate.
- Post-extubation NIV / HFNC: COPD / CHF → NIV cuts reintubation + mortality. Hypoxaemic without hypercapnia → HFNC first-line.
- Reintubation within 48 h = failure (high mortality). Review cause before next trial (volume overload, cardiac, sputum, mental status, upper airway).
🫁 ARDS Management Bundle
1. Lung-protective ventilation (every patient)
TV 6 mL/kg PBW (range 4 – 8 if needed). Use the PBW card above — never actual body weight.
Plateau pressure ≤ 30 cmH₂O (measure 0.5 s inspiratory hold, no spontaneous effort).
Driving pressure (Pplat − PEEP) < 15 cmH₂O — strongest single predictor of mortality (Amato NEJM 2015).
RR 20 – 35 to maintain minute ventilation; permissive hypercapnia OK down to pH ≥ 7.20.
SpO₂ target 88 – 95 %; PaO₂ 55 – 80 (ARDSnet) — avoid hyperoxia.
2. PEEP / FiO₂ titration (ARDSnet lower table)
FiO₂ 0.3 · 0.4 · 0.4 · 0.5 · 0.5 · 0.6 · 0.7 · 0.7 · 0.7 · 0.8 · 0.9 · 0.9 · 0.9 · 1.0
PEEP 5 · 5 · 8 · 8 · 10 · 10 · 10 · 12 · 14 · 14 · 14 · 16 · 18 · 18 – 24
Moderate-severe ARDS: consider higher-PEEP table (ALVEOLI / LOVS / EXPRESS). Titrate to best compliance OR to driving pressure < 15, not to oxygenation alone.
3. Prone positioning — PROSEVA (life-saving in moderate-severe)
Trigger: P/F < 150 on FiO₂ ≥ 0.6 and PEEP ≥ 5 for ≥ 12 h.
Duration: at least 16 h/day × consecutive sessions until P/F ≥ 150 on FiO₂ ≤ 0.6 + PEEP ≤ 10 for 4 h supine.
Mortality benefit: 28-day mortality 16 % vs 32.8 % (NNT 6, PROSEVA NEJM 2013). Needs a trained team; brief sedation and paralysis for the flip. Secure ETT and lines first, protect eyes/pressure points, aspirate before turn.
4. Neuromuscular blockade (short course if severe + asynchrony)
For P/F < 150 with ventilator dyssynchrony despite deep sedation (RASS − 4/− 5):
Cisatracurium 15 mg IV bolus → 37.5 mg/hr infusion × 48 h (ACURASYS protocol).
ROSE trial (2019) showed no mortality benefit vs light sedation — now reserved for severe ARDS with high plateau pressure, dyssynchrony, or difficulty proning. Train-of-four not routinely required at this dose. Stop by 48 h to avoid ICU-acquired weakness.
5. Conservative fluid strategy (FACTT)
After shock resolved (MAP ≥ 60, no vasopressor need), aim for net-zero / negative balance. Use furosemide boluses or infusion if CVP > 4 and UO < 0.5 mL/kg/hr with adequate perfusion.
Benefit: more ventilator-free days (14.6 vs 12.1), shorter ICU stay. No mortality difference — but shorter time on vent.
6. Corticosteroids (moderate-severe, within 14 days)
Dexamethasone 20 mg IV daily × 5 d, then 10 mg × 5 d (DEXA-ARDS, Villar Lancet Resp Med 2020).
COVID-19 ARDS: dexamethasone 6 mg IV/PO × 10 d (RECOVERY).
Avoid if infection unidentified or starting > 14 d from onset. Monitor glucose, infection, bleeding.
7. Rescue therapies (if refractory on bundle above)
Recruitment manoeuvre: brief PEEP 35 – 40 × 40 s or stepwise PEEP escalation — may transiently improve oxygenation; avoid aggressive protocols (ART trial showed harm).
Inhaled vasodilators (iNO 5 – 20 ppm, inhaled epoprostenol 50 ng/kg/min) — oxygenation only, no mortality benefit; bridge to prone/ECMO.
Avoid HFOV in adults (OSCILLATE, OSCAR).
8. VV-ECMO — EOLIA criteria
Refer early (ideally < 7 d of mechanical ventilation):
• P/F < 50 on FiO₂ ≥ 0.8 × 3 h, OR
• P/F < 80 on FiO₂ ≥ 0.8 × 6 h, OR
• pH < 7.25 with PaCO₂ ≥ 60 for > 6 h despite RR 35 and Pplat ≤ 32.
EOLIA (NEJM 2018) + post-hoc Bayesian analysis (Goligher JAMA 2018): mortality 35 % vs 46 %. Contraindications: terminal disease, severe comorbidities, intracranial bleed, prolonged (> 7 d) high-pressure/FiO₂ ventilation.
Use the Murray Lung Injury Score card below to objectively grade severity.
9. Monitoring + weaning
Daily: SBT / spontaneous awakening (SAT) once pressors off, FiO₂ ≤ 0.5, PEEP ≤ 8, Pplat ≤ 25, pH ≥ 7.30, mental status adequate.
Early mobilisation when safe (ABCDEF bundle). Nutrition: enteral < 48 h, trophic feeds initially acceptable (EDEN trial).
Acid–Base / ABG
Primary disorder, compensation, anion gap, Δ-Δ, A–a.
Inputs
Interpretation
Electrolytes
Corrections, osmolality, FWD, K⁺ replacement.
Corrected Calcium
Corrected Na (hyperglycemia)
Osmolal Gap & Toxic Alcohols
Toxic alcohol differential (tap)
- Methanol — HAGMA + ↑gap, retinal/optic Sx, formic acid; antidote: fomepizole, folate, HD if severe.
- Ethylene glycol — HAGMA + ↑gap, Ca-oxalate crystals in urine, AKI; antidote: fomepizole, thiamine + pyridoxine, HD if severe.
- Isopropyl alcohol — ↑gap without HAGMA (ketosis without acidosis); supportive care, HD rarely.
- Propylene glycol — IV lorazepam/phenobarb/TMP-SMX infusions; stop offending agent, HD if severe.
- Mannitol / glycerol / sorbitol — iatrogenic; ↑gap without acidosis.
- Severe ketoacidosis (DKA, AKA, starvation) — mild ↑gap from ketones.
- Lactic acidosis — mild ↑gap from lactate.
Free Water Deficit
Potassium Replacement
⚡ Hyperkalemia Emergency Protocol
1. Stabilise cardiac membrane (within minutes)
Calcium gluconate 10% 30 mL IV over 10 min (or Ca chloride 10% 10 mL via central). Repeat q10 min if ECG changes persist. Onset 1–3 min, duration 30–60 min.
2. Shift K⁺ intracellularly
Insulin 10 units IV + Dextrose 25 g IV (50 mL D50W). Check glucose q1h × 6 — hypoglycaemia common.
Salbutamol 10–20 mg nebulised. Avoid in tachyarrhythmia.
Sodium bicarbonate only if co-existing metabolic acidosis (not routine).
3. Remove K⁺ from body
Furosemide 20–80 mg IV if volume replete + urine output.
Patiromer 8.4 g PO (or SZC/Lokelma 10 g PO) — slow onset.
Haemodialysis if refractory, severe (K > 6.5 unresponsive), AKI with oliguria, or symptomatic.
4. Monitor + root-cause
Continuous ECG; recheck K⁺ at 1 h and q2h. Stop ACEi/ARB/K-sparing diuretics/trimethoprim. Treat AKI, acidosis, rhabdo, tumour lysis.
🩸 DKA / HHS Protocol
1. Fluids (first hour)
0.9% NaCl 15–20 mL/kg IV over 1 h (1–1.5 L adult). Then 250–500 mL/hr adjusted to haemodynamics. Switch to 0.45% NaCl once corrected Na is normal/high.
Add D5 ½ NS when glucose < 250 mg/dL (14 mmol/L) to allow insulin continuation.
2. Insulin
Check K⁺ FIRST. If K⁺ < 3.3 → hold insulin, replace K⁺ first.
Regular insulin 0.1 U/kg IV bolus, then 0.1 U/kg/hr infusion. Target glucose fall 50–75 mg/dL/hr.
When glucose ≤ 200 (DKA) or ≤ 300 (HHS) → cut infusion in half (0.02–0.05 U/kg/hr) and add dextrose.
Transition to subcutaneous when AG closed + patient eating.
3. Potassium (always deplete!)
K⁺ > 5.2 → no replacement, recheck q2h
K⁺ 3.3–5.2 → 20–30 mEq KCl in each litre of IVF
K⁺ < 3.3 → HOLD insulin, give 20–40 mEq/hr until > 3.3
4. Bicarbonate (rarely)
Only if pH < 6.9: 100 mEq NaHCO₃ in 400 mL water + 20 mEq KCl, over 2 h. Not routine — may worsen hypokalaemia + cerebral acidosis.
5. Monitoring + resolution
q1–2h: glucose, electrolytes (K, Mg, Phos), AG, pH. Resolution: AG < 12, HCO₃ > 15, pH > 7.3, glucose < 200. Treat precipitant (infection, missed insulin, MI, pancreatitis).
Renal & Fluids
CrCl, UO, sepsis bolus, maintenance.
Creatinine Clearance
Urine Output
Sepsis Fluid Bolus
Maintenance Fluids (4-2-1)
Transfusion Thresholds
| Product | Trigger | Dose / expected rise |
|---|---|---|
| PRBC — general ICU | Hb < 7 g/dL | 1 unit → ↑ Hb ~ 1 g/dL |
| PRBC — ACS / cardiac | Hb < 8 g/dL | same |
| PRBC — septic shock (early) | Hb < 7 g/dL (TRISS) | same |
| PRBC — active major bleeding | Clinical, target Hb ≥ 7 | See MTP card |
| Platelets — spontaneous bleed risk | < 10 × 10⁹/L | 1 adult dose → ↑ 20 – 40 |
| Platelets — minor procedure, LP, line | < 20 – 50 | same |
| Platelets — major surgery / neurosurg | < 100 | same |
| Platelets — active bleeding | Keep > 50 (> 100 if CNS) | same |
| FFP — INR > 1.5 + bleeding / pre-procedure | INR > 1.5 – 1.7 | 10 – 15 mL/kg |
| Cryoprecipitate | Fibrinogen < 1.5 g/L (bleeding) OR < 2 g/L (obstetric) | 10 units adult → ↑ fib ~ 0.5 g/L |
| PCC (4-factor) | Warfarin / factor Xa reversal + major bleed | 25 – 50 U/kg + vit K 10 mg IV |
TRALI vs TACO — differential (tap)
| Feature | TRALI | TACO |
|---|---|---|
| Onset | < 6 h post-transfusion | < 6 h, often during |
| Mechanism | Anti-HLA / neutrophil Ab → non-cardiogenic pulm oedema | Volume overload — cardiogenic |
| BP | Hypotension (classic) | Hypertension (classic) |
| BNP | Normal | Elevated (> 1 200 pg/mL) |
| LV function | Normal | Reduced / overloaded |
| Response to diuretics | Poor | Good |
| Treatment | Supportive, lung-protective vent, report donor | Diurese, slow / stop transfusion |
Nutrition Targets (ICU)
Refeeding risk + practical tips (tap)
- Refeeding risk (NICE): BMI < 16 · ≥ 15 % weight loss in 3 – 6 mo · little/no intake > 10 d · low K/Mg/PO₄ before feeding. Start at 5 – 10 kcal/kg/d, advance slowly over 4 – 7 d; replace K, Mg, PO₄; thiamine 100 – 300 mg IV before feeding.
- EDEN (NEJM 2012): trophic feeds (10 – 20 mL/hr) non-inferior to full feeds for 6 d in ARDS — ventilator-free days equal.
- TARGET (NEJM 2018): 1.5 kcal/mL concentrated feed non-inferior to 1.0 kcal/mL in critically ill — no mortality or infection difference.
- Protein — critical illness: 1.3 g/kg/d (ASPEN/SCCM); 1.5 – 2.0 if burns, trauma, sepsis, CRRT, polytrauma, pressure injury.
- Parenteral nutrition if enteral contraindicated (bowel obstruction, GI bleed, severe ileus) and ≥ 7 d expected NPO — start low (EPaNIC NEJM 2011).
Parkland Formula (burns)
Rule of Nines — adult TBSA reference (tap)
- Head & neck — 9 %
- Each upper limb — 9 %
- Each lower limb — 18 %
- Anterior trunk — 18 %
- Posterior trunk — 18 %
- Perineum — 1 %
- Palm (patient's own) — ~ 1 % (handy for patchy burns)
🩸 Massive Transfusion Protocol (MTP)
1. Ratio-based resuscitation (1 : 1 : 1)
For every 6 units PRBC → 6 units FFP → 1 adult dose platelets (= 1 apheresis unit or 6-pack).
Order by MTP pack. Resist crystalloid > 1 L (dilutes clotting factors).
2. Adjunctive haemostatic drugs
Tranexamic acid 1 g IV over 10 min, then 1 g over 8 h — give within 3 h of trauma (CRASH-2).
Fibrinogen replacement: cryoprecipitate 10 units (adult) or fibrinogen concentrate 2–4 g if fibrinogen < 1.5 g/L.
Prothrombin complex (PCC) 25–50 U/kg for warfarin / Xa reversal + major haemorrhage.
DDAVP 0.3 mcg/kg IV if uraemic bleeding / aspirin.
3. Correct the lethal triad
Hypothermia: warm all fluids (37 °C), forced-air warmer, cover head.
Acidosis: treat shock first; bicarbonate only if pH < 7.1 persisting.
Coagulopathy: see ratio above; add TXA + fibrinogen + Ca.
4. Monitor + endpoints
q 30 min: TEG/ROTEM if available, INR, fibrinogen, ionised Ca (target > 1.1 — give 1 g Ca gluconate per 4 units blood), K⁺, lactate, temp.
Stop MTP when haemodynamically stable, SBP > 90 for 30 min, HR < 110, no further transfusion requirement in 30 min, source controlled.
5. Target values
Hb 7–9 · platelets > 50 (> 100 if head injury / ongoing haemorrhage) · fibrinogen > 1.5–2 · INR < 1.5 · ionised Ca > 1.1 · temp > 36 °C · pH > 7.2 · base deficit < 6.
Clinical Scores
Live scoring with interpretation.
GCS
qSOFA
SOFA
CHA₂DS₂-VASc
HAS-BLED
Wells (PE)
RASS
Modified Duke Criteria
APACHE II
HEART Score
TIMI (UA/NSTEMI)
CURB-65
ICH Score
NIHSS
Hunt & Hess (SAH)
Modified Fisher (SAH)
Child-Pugh
CAM-ICU
Padua VTE
Murray Lung Injury Score
MELD-Na
Vancomycin AUC₂₄ (bedside estimate)
Shift Notes
Scratchpad, stored unencrypted in this browser only. Don’t write names, MRNs, dates of birth or bed numbers: ward computers are often shared.
Antidotes
Toxicology reversal · overdose antidotes · NMB reversal.
🚨 Rapid Sequence Intubation
Bedside protocol — the 7 P's, all induction agents, paralytics, pre-treatment, and reversal.
The 7 P's
RSI Drug Reference
Doses at a glance — pre-treat → induce → paralyse → reverse.
Neuroprotective Strategy
Bedside bundle for TBI, SAH, ischemic stroke, ICH and post-arrest care. Check it against your unit’s protocol.
⚡ Status Epilepticus Protocol
0 – 5 min · Stabilisation
ABC · O₂ · IV access · attach monitor · finger-stick glucose immediately.
Labs: electrolytes (Na, Mg, Ca, PO₄), BUN, LFT, CBC, toxicology, AED levels, pregnancy test (women of reproductive age), ABG, blood culture if febrile.
If hypoglycaemia → thiamine 100 mg IV THEN dextrose 25 g IV (D50 50 mL).
5 – 20 min · Initial therapy (benzodiazepine)
Choose ONE, give full dose, repeat ONCE if seizures continue:
• Midazolam 10 mg IM (adult ≥ 40 kg) — preferred when no IV, superior to IV lorazepam in RAMPART trial.
• Lorazepam 0.1 mg/kg IV (max 4 mg) over 2 min — gold standard with IV access.
• Diazepam 0.15 – 0.2 mg/kg IV (max 10 mg) over 2 min — short duration, follow with 2nd-line.
Underdosing is the commonest error — give the FULL dose.
20 – 40 min · Second-line therapy
Pick ONE (no evidence of superiority between the three — ESETT trial):
• Levetiracetam 60 mg/kg IV (max 4 500 mg) over 10 min — fewest drug interactions.
• Fosphenytoin 20 mg PE/kg IV (max 1 500 mg PE) at ≤ 150 mg PE/min — cardiac monitor, avoid in heart block / torsades.
• Valproate 40 mg/kg IV (max 3 000 mg) over 10 min — avoid in hepatic failure, mitochondrial disease, pregnancy.
40 – 60 min · Refractory status — intubate + anaesthetic infusion
Intubate (RSI tab). Start continuous EEG. Choose ONE anaesthetic — target burst suppression × 24 – 48 h, then wean:
• Midazolam 0.2 mg/kg bolus → 0.05 – 2 mg/kg/hr infusion (titrate every 5 min).
• Propofol 1 – 2 mg/kg bolus → 20 – 200 μg/kg/min (watch for PRIS at > 80 μg/kg/min > 48 h).
• Pentobarbital 5 – 15 mg/kg bolus (≤ 50 mg/min) → 0.5 – 5 mg/kg/hr — hypotension, ileus common, prolonged recovery.
Super-refractory (> 24 h) — adjuncts
Ketamine 1 – 5 mg/kg/hr · hypothermia 32 – 35 °C · magnesium 4 g IV (eclampsia) · pyridoxine 70 mg/kg (INH toxicity, infants) · ketogenic diet · immunotherapy (steroids, IVIG, plasmapheresis) · surgery for lesional cases.
Monitoring + special situations
Continuous EEG mandatory in refractory + after convulsions stop (non-convulsive SE in ≥ 20 % of persistent coma post-SE).
Eclampsia: MgSO₄ 4 – 6 g IV loading → 1 – 2 g/hr; deliver fetus.
Alcohol withdrawal: benzodiazepines + thiamine; avoid phenytoin (ineffective).
Toxic: INH → pyridoxine · TCA → NaHCO₃ · theophylline → HD · cocaine → benzos.
🧠 ABCDEF ICU Liberation Bundle
A · Assess, prevent and manage PAIN
Tool: CPOT ≥ 3 (non-verbal) OR NRS ≥ 4 (verbal) = pain.
Treat pain FIRST before adding sedation (analgo-sedation).
First-line: fentanyl 25 – 100 μg/hr infusion, titrate to CPOT < 3. Avoid morphine in renal failure (metabolite accumulation).
Adjuncts: paracetamol 1 g IV q 6 h · ketamine 0.1 – 0.5 mg/kg/hr for opioid-sparing · gabapentin / regional blocks if appropriate. Avoid long-term NSAIDs in critical illness.
B · BOTH Spontaneous Awakening (SAT) + Spontaneous Breathing Trial (SBT)
SAT safety: no active seizures, no alcohol withdrawal, no neuromuscular blockade, no agitation on current sedation, no myocardial ischaemia in prior 24 h, no ↑ICP.
SAT = stop sedation (± opioid continued for pain). If RASS ≥ − 1 within 4 h → go to SBT.
SBT: see the Weaning Readiness card in Ventilator tab for criteria + RSBI.
Awake Breathing Controlled trial (ABC, Girard Lancet 2008): more vent-free days (14.7 vs 11.6), lower 1-yr mortality (44 vs 58 %).
C · Choice of analgesia and sedation
Target light sedation: RASS 0 to − 2 unless specific indication for deeper (ARDS prone, severe asynchrony, ↑ICP, status epilepticus).
Prefer non-benzodiazepines:
• Propofol 5 – 50 μg/kg/min (watch PRIS > 80 μg/kg/min > 48 h)
• Dexmedetomidine 0.2 – 1.5 μg/kg/hr (SPICE-III, MENDS2: non-inferior to propofol, less delirium in some trials)
Avoid benzodiazepine infusions (midazolam, lorazepam) unless alcohol/benzo withdrawal or refractory status.
Reassess sedation level + need q 4 h.
D · Delirium — assess, prevent, manage
Assess: CAM-ICU each shift (see Scores tab) + RASS first.
Prevent: re-orientate, open blinds in day / dim at night, hearing aids / glasses on, early mobility, family at bedside, pain + sedation per above, avoid tethers.
Manage (DELIRIUMS mnemonic — find a cause): Drugs (anticholinergics, steroids, opioids, benzos) · Electrolytes / endocrine (Na, Ca, Mg, glucose, thyroid) · Low O₂ (hypoxia, hypoperfusion, anaemia, MI) · Infection / sepsis · Retention (urinary, faecal) · Ictal / post-ictal · Under-hydration / under-nutrition · Metabolic (uraemia, hepatic encephalopathy, acid-base) · Subdural / stroke / CNS.
Pharmacology: antipsychotics (haloperidol 2 – 5 mg IV q 4 – 6 h, olanzapine, quetiapine 25 – 100 mg BID) only for severe agitation / safety — no mortality benefit (MIND-USA). Dexmedetomidine for hyperactive delirium at night.
E · Early mobility and exercise
Begin ROM within 24 – 48 h of ICU admit when haemodynamically stable (MAP ≥ 65 off escalating pressors, FiO₂ ≤ 0.6, PEEP ≤ 10, no active ischaemia / arrhythmia).
Progression: passive ROM → active ROM → sitting edge of bed → standing → marching → walking in room → walking in corridor.
Needs 2 – 3 staff + physio + RT; portable ventilator OK. Mobility within 72 h cuts ICU LOS by 1.5 d (Schweickert Lancet 2009).
F · Family engagement + empowerment
Open / flexible visitation. Involve family in rounds, delirium prevention (orientation, familiar objects, voice recordings), SAT/SBT coaching.
Daily communication: diagnosis, prognosis, goals of care, estimated LOS. Document family meetings. Offer palliative care consult when prognosis guarded.
ICU diary, follow-up clinic reduces PTSD (RACHEL, Jones et al.).
Sepsis & Septic Shock
Surviving Sepsis Campaign 2021 — bedside bundle, resuscitation, pressors, source control, adjuncts.
About & evidence
What this tool is for, what it rests on, and how to report a problem.
Evidence and limits
- Who it is for
- ICU/CCU doctors, pharmacists and nurses who already know these drugs and scores and want quick arithmetic at the bedside: infusion rates, renal dose bands, ventilator targets, acid–base workup, electrolyte corrections and common scores.
- What it does not do
- Choose a drug or a dose for a patient, replace a pharmacy check, know your unit’s drug concentrations, or apply every renal or hepatic adjustment.
- Methods and evidence
- Each calculator applies a published formula or score as written (Cockcroft–Gault, Winters, Berlin, ARDSnet, SOFA, RASS and others). Dose ranges come from standard ICU references and guidelines. Where a calculator has a source, it is printed under the result; the full list is under Clinical references.
- Validation and known limitations
- Not prospectively or independently validated, and the code and dose tables have not been externally audited.
- Decision support only. It does not replace clinical judgement, local protocols or the drug label.
- Default concentrations are common preparations, not necessarily yours. If your bag differs, the mL/hr is wrong.
- Cockcroft–Gault is unreliable when creatinine is changing, at extremes of body weight and in augmented renal clearance.
- Some results have no individual citation yet: MAP, shock index, CPP, anion gap, A–a gradient, corrected Ca and Na, osmolality, K⁺ replacement, maintenance fluids, GCS, qSOFA, RSI, antidotes and neuroprotection.
- Not a regulated medical device.
- Version
- 1.5.9 · last reviewed 05 November 2026.
- Report a suspected error
- Say what you entered, what the app showed and what you expected, with a source if you have one. Leave out patient identifiers.
Designed by
📧 Contact Us
Data on this device
- What is stored
- One unencrypted browser storage entry (
localStorage, keynajmICU_v2) holding, for each patient pill, its label, patient bar (weight, height, age, sex, creatinine), values typed into calculators, score selections and shift notes; plus and display settings (units, last tab, search filters, whether you have seen the welcome screen). The offline cache holds only the app’s own files. - What leaves the device
- Nothing you enter, unless you choose to send it. Smart Assistant sends a prompt only when you press “Open in Claude” or “Open in ChatGPT”, and shift notes go with it only if you tick the box. Separately, page views are counted with GoatCounter: no cookies and none of your entries, and it is skipped if your browser sends Do Not Track.
- Shared computers
- Anyone using this browser profile can read what is saved. Don’t enter names, MRNs or dates of birth. On a shared device, keep pill labels neutral (P1, P2) rather than bed numbers, and clear the data at the end of your shift.
Install and offline use
- iPhone or iPad (Safari)
- Tap Share, then “Add to Home Screen”.
- Android (Chrome)
- Open the ⋮ menu, then “Install app” (or “Add to Home screen”).
- Desktop (Chrome or Edge)
- Use the install icon at the right of the address bar.
- Offline
- After one online visit, all calculators, scores, references and the notes pad work without a connection. Updates load the next time you open the app online.
- Needs a connection
- Smart Assistant’s “Open in Claude” and “Open in ChatGPT” (they open claude.ai or chatgpt.com).
- The Source link (GitHub) and email links (your mail app).
- The page-view count, which is simply skipped offline.
Clinical References
Changelog
1.5.9 · 05 November 2026
- Custom domain — Najm ICUCalc now lives at
https://icucalc.thetract.org/. CNAME file + sitemap.xml + robots.txt + canonical + Open Graph all point at the new domain. Old github.io URL continues to work via Pages redirect. - About card: added LinkedIn + GitHub rows.
- Formula audit: 17 core calculators verified against published worked examples (CrCl, MAP, QTc Bazett, AG, osmolal gap, P/F, corrected Ca, driving pressure, ROX, MELD-Na, Parkland, Devine IBW, Mosteller BSA, RSBI, Mifflin REE).
1.5.8 · 05 November 2026
- Per-card source citations — every formula now shows its reference under the card itself, not only in the Clinical References list. Added: Bazett / Fridericia / Framingham (QTc), Allgöwer & Buri + Liu 2012 (shock index), Brain Trauma Foundation 2017 (CPP), Payne 1973 (corrected Ca), Katz 1973 + Hillier 1999 (corrected Na), Kraft 2005 (K⁺ replacement), Holliday & Segar 1957 (4-2-1 maintenance), Teasdale & Jennett 1974 (GCS card), Singer Sepsis-3 2016 (qSOFA card).
- About card: added Role (Neurology & Neurocritical Care), Affiliation (KMGH / KFMC), Website link (thetract.org), and a one-line "Why this app".
1.5.7 · 01 November 2026
- New protocol: ABCDEF ICU Liberation Bundle red-themed card in Neuroprotection — Assess pain (CPOT/NRS), Both SAT + SBT, Choice of light sedation (RASS 0 to − 2, prefer non-benzos), Delirium (CAM-ICU + DELIRIUMS mnemonic), Early mobility, Family engagement.
- New calculator: Weaning Readiness + RSBI in Ventilator tab — SBT eligibility, pass criteria, cuff-leak test, post-extubation HFNC/NIV guidance.
- New card: Transfusion Thresholds in Renal & Fluids — Hb / platelet / FFP / cryo / PCC triggers with expected rise, plus TRALI vs TACO comparison table (onset, mechanism, BP, BNP, LV, treatment).
- New calculator: Nutrition Targets in Renal & Fluids — Mifflin-St Jeor REE × stress factor, protein 1.2 – 2.0 g/kg, refeeding risk and tips (EDEN, TARGET, EPaNIC).
- References: added Yang & Tobin 1991 (RSBI), Thille HFNC 2019, PADIS 2018, ICU Liberation (Pun 2019), ABC trial 2008, Schweickert 2009, MIND-USA 2018, TRICC 1999, TRISS 2014, AABB 2016, ISBT TRALI 2019, ASPEN/SCCM 2016, EDEN 2012, TARGET 2018.
1.5.6 · 05 November 2026
- New protocol: ARDS Management Bundle red-themed card in Ventilator tab — Berlin severity, lung-protective ventilation (TV 6/PBW, Pplat ≤ 30, DP < 15, permissive hypercapnia pH ≥ 7.20), ARDSnet lower PEEP/FiO₂ ladder, PROSEVA prone criteria (P/F < 150, 16 h/day), ACURASYS/ROSE neuromuscular blockade, FACTT conservative fluid, DEXA-ARDS/RECOVERY steroids, rescue therapies (recruitment, iNO), EOLIA ECMO criteria, SBT/weaning.
- New score: Murray Lung Injury Score — 4-item (CXR, P/F, PEEP, compliance); average > 2.5 = ECMO criterion.
- References: added Murray 1988, Guérin PROSEVA NEJM 2013, Papazian ACURASYS NEJM 2010, PETAL ROSE NEJM 2019, Wiedemann FACTT NEJM 2006, Villar DEXA-ARDS Lancet Resp Med 2020, Combes EOLIA NEJM 2018, Amato NEJM 2015.
1.5.5 · 05 November 2026
- Tier-2 clinical additions — seven new scores and three new calculators:
- New scores: NIHSS (11-item, 0–42) · Hunt & Hess (SAH clinical grade 1–5) · Modified Fisher (SAH CT, vasospasm risk) · Child-Pugh (A/B/C, 1-yr survival) · CAM-ICU (delirium screen) · Padua VTE (prophylaxis trigger ≥ 4).
- New calculators: MELD-Na (UNOS 2016 formula, 90-day mortality bands) · Vancomycin AUC₂₄ bedside estimate (ASHP/IDSA 2020 target 400–600 mg·h/L) · Parkland burns formula (4 mL·kg·%TBSA LR split 8 h/16 h, Rule of Nines).
- New protocol: Status Epilepticus red-themed card in Neuroprotection — timed escalation (0–5 min stabilisation → 5–20 benzos → 20–40 min 2nd-line → 40–60 min anaesthetic infusion → super-refractory adjuncts).
- References: added Brott 1989 (NIHSS), Hunt & Hess 1968, Frontera 2006 (mod Fisher), Pugh 1973, Kim 2008 (MELD-Na), Ely 2001 (CAM-ICU), Barbar 2010 (Padua), Glauser 2016 + Kapur ESETT 2019 + Silbergleit RAMPART 2012 (status epilepticus), Baxter & Shires 1968 (Parkland), ABA 2016 (burn transfer).
1.5.4 · 05 November 2026
- Osmolal gap card rebuilt: severity bands (normal / mild / moderate / severe), parallel calc with and without ethanol, toxic-alcohol differential diagnosis (methanol, ethylene glycol, isopropyl, propylene glycol, mannitol) with escalation plan (fomepizole + HD trigger).
- References: added Krasowski 2012 (osmolal gap performance), Kraut & Mullins NEJM 2018 (toxic alcohols), Purssell 2001 (ethanol correction).
1.5.3 · 30 October 2026
- Added author's phone / WhatsApp (+966 56 476 2990) to the About card.
- Version and last-reviewed date brought up to date across the app.
1.5.1 · 05 November 2026
- References expanded to 11 sections and 57 citations (Sepsis, ARDS, Trauma/MT, Scores, Formulas, Antibiotics, Toxicology, Hyperkalaemia/DKA, Neuroprotection, Nephrology, general ICU).
- Clinical references now rendered with cyan section headings for easier scanning.
1.5.0 · 05 November 2026
- Tier-1 batch for daily ICU/ED use:
- HEART Score (6-week MACE for undifferentiated chest pain).
- TIMI (UA/NSTEMI) for 14-day death/MI/urgent-revasc risk.
- CURB-65 for pneumonia severity triage (outpatient / ward / ICU).
- ICH Score for 30-day mortality in spontaneous intracerebral haemorrhage.
- QTc calculator (Bazett + Fridericia + Framingham) in Hemodynamics, with torsades warning ≥ 500 ms.
- ROX Index in Ventilator for HFNC success prediction (4.88 / 3.85 cut-offs).
- Hyperkalaemia Emergency Protocol — 4-step pathway (stabilise · shift · remove · monitor).
- DKA / HHS Protocol — fluids → insulin → K replacement → bicarb thresholds → resolution.
- Massive Transfusion Protocol — 1:1:1 ratio, TXA, lethal-triad fixes, target values.
1.4.3 · 05 November 2026
- APACHE II score added to Scores with mortality band interpretation.
- Sepsis & Septic Shock tab added — full Surviving Sepsis Campaign 2021 bundle (Hour-1, fluids, pressor ladder, empiric abx, source control, steroids, vent, glucose, transfusion, RRT, nutrition, prophylaxis, procalcitonin, when-to-call).
1.4.2 · 25 October 2026
- Modified Duke Criteria for infective endocarditis — categorical interpretation (Definite / Possible / Rejected).
- tallyScore() now passes raw selections to score interpreters so categorical scoring works alongside simple sums.
1.4.1 · 9 October 2026
- Patient pills are now real, keyboard-reachable buttons (switch, rename, remove), with screen-reader labels.
- “Clear” in the patient bar now clears the active patient’s calculator inputs and scores as well, so a new patient in the same slot never inherits old values.
- Rename asks for a short label and warns against names and MRNs; the data notice now covers multiple patients.
- Version shown consistently everywhere.
1.4.0 · 9 October 2026
- Patient switcher: P1, P2, P3…, each with its own patient bar, inputs, scores and notes; pills can be renamed.
1.3.1 · 9 October 2026
- Evidence and limits panel on the welcome screen and under About & evidence.
- Source line under each calculator that has a published reference.
- Install, offline and stored-data notes; “Clear saved data” moved beside them.
- Page-view counter now skipped under Do Not Track; privacy policy corrected to disclose it.
- “Intelligent assistant” wording removed.
1.3.0 · 9 October 2026
- Shift notes no longer attached to AI links by default; opt-in with a no-identifiers check.
- “What leaves this device” note in Smart Assistant.
- Unsupported claims (“precise”, “latest guidelines”) removed.
- Google Fonts dropped; contact email unified to contact@thetract.org.
1.2.0 · 28–29 July 2026
- Rocuronium and cisatracurium infusions, Neuroprotective Strategy tab, contact block.
- Production service worker; manifest paths made relative.
1.1.0 · 28 July 2026
- High-contrast inputs and missing-input hints; eight more neuromuscular blockers.
- RSI moved to its own tab with the 7 P’s; creatinine input width fixed.